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Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency

Although thousands of breast cancer cells disseminate and home to bone marrow until primary surgery, usually less than a handful will succeed in establishing manifest metastases months to years later. To identify signals that support survival or outgrowth in patients, we profile rare bone marrow-der...

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Detalles Bibliográficos
Autores principales: Werner-Klein, Melanie, Grujovic, Ana, Irlbeck, Christoph, Obradović, Milan, Hoffmann, Martin, Koerkel-Qu, Huiqin, Lu, Xin, Treitschke, Steffi, Köstler, Cäcilia, Botteron, Catherine, Weidele, Kathrin, Werno, Christian, Polzer, Bernhard, Kirsch, Stefan, Gužvić, Miodrag, Warfsmann, Jens, Honarnejad, Kamran, Czyz, Zbigniew, Feliciello, Giancarlo, Blochberger, Isabell, Grunewald, Sandra, Schneider, Elisabeth, Haunschild, Gundula, Patwary, Nina, Guetter, Severin, Huber, Sandra, Rack, Brigitte, Harbeck, Nadia, Buchholz, Stefan, Rümmele, Petra, Heine, Norbert, Rose-John, Stefan, Klein, Christoph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536220/
https://www.ncbi.nlm.nih.gov/pubmed/33020483
http://dx.doi.org/10.1038/s41467-020-18701-4