Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division

The energetic demands of a cell are believed to increase during mitosis, but the rates of ATP synthesis and consumption during mitosis have not been quantified. Here, we monitor mitochondrial membrane potential of single lymphocytic leukemia cells and demonstrate that mitochondria hyperpolarize from...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Joon Ho, Katsikis, Georgios, Li, Zhaoqi, Sapp, Kiera M., Stockslager, Max A., Lim, Daniel, Vander Heiden, Matthew G., Yaffe, Michael B., Manalis, Scott R., Miettinen, Teemu P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536222/
https://www.ncbi.nlm.nih.gov/pubmed/33020492
http://dx.doi.org/10.1038/s41467-020-18769-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536222/
https://www.ncbi.nlm.nih.gov/pubmed/33020492
http://dx.doi.org/10.1038/s41467-020-18769-y

Ejemplares similares