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Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division
The energetic demands of a cell are believed to increase during mitosis, but the rates of ATP synthesis and consumption during mitosis have not been quantified. Here, we monitor mitochondrial membrane potential of single lymphocytic leukemia cells and demonstrate that mitochondria hyperpolarize from...
Autores principales: | Kang, Joon Ho, Katsikis, Georgios, Li, Zhaoqi, Sapp, Kiera M., Stockslager, Max A., Lim, Daniel, Vander Heiden, Matthew G., Yaffe, Michael B., Manalis, Scott R., Miettinen, Teemu P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536222/ https://www.ncbi.nlm.nih.gov/pubmed/33020492 http://dx.doi.org/10.1038/s41467-020-18769-y |
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