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Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD

Nonalcoholic fatty liver disease (NAFLD) is associated with obesity but also found in non-obese individuals. Gut microbiome profiles of 171 Asians with biopsy-proven NAFLD and 31 non-NAFLD controls are analyzed using 16S rRNA sequencing; an independent Western cohort is used for external validation....

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Detalles Bibliográficos
Autores principales: Lee, Giljae, You, Hyun Ju, Bajaj, Jasmohan S., Joo, Sae Kyung, Yu, Junsun, Park, Seoyeon, Kang, Hyena, Park, Jeong Hwan, Kim, Jung Ho, Lee, Dong Hyeon, Lee, Seonhwa, Kim, Won, Ko, GwangPyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536225/
https://www.ncbi.nlm.nih.gov/pubmed/33020474
http://dx.doi.org/10.1038/s41467-020-18754-5