Cdc6 disruption leads to centrosome abnormalities and chromosome instability in pancreatic cancer cells

Cell division cycle 6 (Cdc6) plays key roles in regulating DNA replication, and activation and maintenance of cell cycle check points. In addition, Cdc6 exerts oncogenic properties via genomic instability associated with incomplete DNA replication. This study aimed to examine the effects of Cdc6 on...

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Detalles Bibliográficos
Autores principales: Youn, Yuna, Lee, Jong-chan, Kim, Jaihwan, Kim, Jae Hyeong, Hwang, Jin-Hyeok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536414/
https://www.ncbi.nlm.nih.gov/pubmed/33020506
http://dx.doi.org/10.1038/s41598-020-73474-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536414/
https://www.ncbi.nlm.nih.gov/pubmed/33020506
http://dx.doi.org/10.1038/s41598-020-73474-6

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