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Immunological fingerprint of 4CMenB recombinant antigens via protein microarray reveals key immunosignatures correlating with bactericidal activity

Serogroup B meningococcus (MenB) is a leading cause of meningitis and sepsis across the world and vaccination is the most effective way to protect against this disease. 4CMenB is a multi-component vaccine against MenB, which is now licensed for use in subjects >2 months of age in several countrie...

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Detalles Bibliográficos
Autores principales: Bartolini, E., Borgogni, E., Bruttini, M., Muzzi, A., Giuliani, M., Iozzi, S., Petracca, R., Martinelli, M., Bonacci, S., Marchi, S., Brettoni, C., Donati, C., Torricelli, G., Guidotti, S., Domina, M., Beninati, C., Teti, G., Felici, F., Rappuoli, R., Castellino, F., Del Giudice, G., Masignani, V., Pizza, M., Maione, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536418/
https://www.ncbi.nlm.nih.gov/pubmed/33020485
http://dx.doi.org/10.1038/s41467-020-18791-0