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Inferring Gene-by-Environment Interactions with a Bayesian Whole-Genome Regression Model
The contribution of gene-by-environment (GxE) interactions for many human traits and diseases is poorly characterized. We propose a Bayesian whole-genome regression model for joint modeling of main genetic effects and GxE interactions in large-scale datasets, such as the UK Biobank, where many envir...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536582/ https://www.ncbi.nlm.nih.gov/pubmed/32888427 http://dx.doi.org/10.1016/j.ajhg.2020.08.009 |