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Knockdown of miR-124 Reduces Depression-like Behavior by Targeting CREB1 and BDNF

OBJECTIVE: As a brain-specific microRNA, the mechanism of miR-124 in depression has not been clarified so far. The present study aimed to explore the role of miR-124 in depression and its potential targets. METHODS: The depression model was first replicated by the chronic unpredictable mild stress (...

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Detalles Bibliográficos
Autores principales: Yang, Wei, Liu, Min, Zhang, Qianwei, Zhang, Jiahua, Chen, Jun, Chen, Qiaoyun, Suo, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536798/
https://www.ncbi.nlm.nih.gov/pubmed/32189593
http://dx.doi.org/10.2174/1567202617666200319141755