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A dCas9-Based System Identifies a Central Role for Ctf19 in Kinetochore-Derived Suppression of Meiotic Recombination

In meiosis, crossover (CO) formation between homologous chromosomes is essential for faithful segregation. However, misplaced meiotic recombination can have catastrophic consequences on genome stability. Within pericentromeres, COs are associated with meiotic chromosome missegregation. In organisms...

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Detalles Bibliográficos
Autores principales: Kuhl, Lisa-Marie, Makrantoni, Vasso, Recknagel, Sarah, Vaze, Animish N., Marston, Adele L., Vader, Gerben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536843/
https://www.ncbi.nlm.nih.gov/pubmed/32843356
http://dx.doi.org/10.1534/genetics.120.303384