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T-cell agonists in cancer immunotherapy

Cancer cells can evade immune surveillance in the body. However, immune checkpoint inhibitors can interrupt this evasion and enhance the antitumor activity of T cells. Other mechanisms for promoting antitumor T-cell function are the targeting of costimulatory molecules expressed on the surface of T...

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Detalles Bibliográficos
Autores principales: Choi, Yeonjoo, Shi, Yaoyao, Haymaker, Cara L, Naing, Aung, Ciliberto, Gennaro, Hajjar, Joud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537335/
https://www.ncbi.nlm.nih.gov/pubmed/33020242
http://dx.doi.org/10.1136/jitc-2020-000966