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Pathways for nicotinic receptor desensitization
Nicotinic acetylcholine receptors (AChRs) are ligand-gated ion channels that generate transient currents by binding agonists and switching rapidly between closed- and open-channel conformations. Upon sustained exposure to ACh, the cell response diminishes slowly because of desensitization, a process...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537344/ https://www.ncbi.nlm.nih.gov/pubmed/32910188 http://dx.doi.org/10.1085/jgp.202012639 |