Single-cell analysis of germinal-center B cells informs on lymphoma cell of origin and outcome

In response to T cell–dependent antigens, mature B cells are stimulated to form germinal centers (GCs), the sites of B cell affinity maturation and the cell of origin (COO) of most B cell lymphomas. To explore the dynamics of GC B cell development beyond the known dark zone and light zone compartmen...

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Detalles Bibliográficos
Autores principales: Holmes, Antony B., Corinaldesi, Clarissa, Shen, Qiong, Kumar, Rahul, Compagno, Nicolo, Wang, Zhong, Nitzan, Mor, Grunstein, Eli, Pasqualucci, Laura, Dalla-Favera, Riccardo, Basso, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537389/
https://www.ncbi.nlm.nih.gov/pubmed/32603407
http://dx.doi.org/10.1084/jem.20200483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537389/
https://www.ncbi.nlm.nih.gov/pubmed/32603407
http://dx.doi.org/10.1084/jem.20200483

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