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Single-cell analysis of germinal-center B cells informs on lymphoma cell of origin and outcome
In response to T cell–dependent antigens, mature B cells are stimulated to form germinal centers (GCs), the sites of B cell affinity maturation and the cell of origin (COO) of most B cell lymphomas. To explore the dynamics of GC B cell development beyond the known dark zone and light zone compartmen...
Autores principales: | Holmes, Antony B., Corinaldesi, Clarissa, Shen, Qiong, Kumar, Rahul, Compagno, Nicolo, Wang, Zhong, Nitzan, Mor, Grunstein, Eli, Pasqualucci, Laura, Dalla-Favera, Riccardo, Basso, Katia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537389/ https://www.ncbi.nlm.nih.gov/pubmed/32603407 http://dx.doi.org/10.1084/jem.20200483 |
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