Lipocalin-2 counteracts metabolic dysregulation in obesity and diabetes

Regulation of food intake is a recently identified endocrine function of bone that is mediated by Lipocalin-2 (LCN2). Osteoblast-secreted LCN2 suppresses appetite and decreases fat mass while improving glucose metabolism. We now show that serum LCN2 levels correlate with insulin levels and β-cell fu...

Descripción completa

Detalles Bibliográficos
Autores principales: Mosialou, Ioanna, Shikhel, Steven, Luo, Na, Petropoulou, Peristera Ioanna, Panitsas, Konstantinos, Bisikirska, Brygida, Rothman, Nyanza J., Tenta, Roxane, Cariou, Bertrand, Wargny, Matthieu, Sornay-Rendu, Elisabeth, Nickolas, Thomas, Rubin, Mishaela, Confavreux, Cyrille B., Kousteni, Stavroula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537391/
https://www.ncbi.nlm.nih.gov/pubmed/32639539
http://dx.doi.org/10.1084/jem.20191261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537391/
https://www.ncbi.nlm.nih.gov/pubmed/32639539
http://dx.doi.org/10.1084/jem.20191261

Ejemplares similares