AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer

Recently, a transcriptome-based consensus molecular subtype (CMS) classification of colorectal cancer (CRC) has been established, which may ultimately help to individualize CRC therapy. However, the lack of animal models that faithfully recapitulate the different molecular subtypes impedes adequate...

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Detalles Bibliográficos
Autores principales: Varga, Julia, Nicolas, Adele, Petrocelli, Valentina, Pesic, Marina, Mahmoud, Abdelrahman, Michels, Birgitta E., Etlioglu, Emre, Yepes, Diego, Häupl, Björn, Ziegler, Paul K., Bankov, Katrin, Wild, Peter J., Wanninger, Stefan, Medyouf, Hind, Farin, Henner F., Tejpar, Sabine, Oellerich, Thomas, Ruland, Jürgen, Siebel, Christian W., Greten, Florian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537393/
https://www.ncbi.nlm.nih.gov/pubmed/32749453
http://dx.doi.org/10.1084/jem.20191515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537393/
https://www.ncbi.nlm.nih.gov/pubmed/32749453
http://dx.doi.org/10.1084/jem.20191515

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