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Noncanonical STAT3 activity sustains pathogenic Th17 proliferation and cytokine response to antigen
The STAT3 signaling pathway is required for early Th17 cell development, and therapies targeting this pathway are used for autoimmune disease. However, the role of STAT3 in maintaining inflammatory effector Th17 cell function has been unexplored. Th17(ΔSTAT3) mice, which delete STAT3 in effector Th1...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537401/ https://www.ncbi.nlm.nih.gov/pubmed/32697822 http://dx.doi.org/10.1084/jem.20191761 |