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B7-H4 Inhibits the Development of Primary Sjögren's Syndrome by Regulating Treg Differentiation in NOD/Ltj Mice

BACKGROUND: This study is aimed at exploring the role of B7-H4 in the pathogenesis of primary Sjögren's syndrome (pSS) in NOD/Ltj mouse. METHODS: B7-H4 expression in salivary glands was examined by IHC, and lymphocyte infiltration was showed by H&E. Next, anti-B7-H4 mAb or immunoglobulin is...

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Detalles Bibliográficos
Autores principales: Zheng, Xu, Wang, Qikai, Yuan, Xiang, Zhou, Yingbo, Chu, Hui, Wang, Guosheng, Li, Xiangpei, Wang, Yiping, Wei, Li, Wang, Li, Li, Xiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537676/
https://www.ncbi.nlm.nih.gov/pubmed/33062721
http://dx.doi.org/10.1155/2020/4896727