Lupeol Counteracts the Proinflammatory Signalling Triggered in Macrophages by 7-Keto-Cholesterol: New Perspectives in the Therapy of Atherosclerosis

Macrophage activation and polarization play a central role in atherosclerotic plaque fate. The M1/M2 activation phenotypes represent two profiles of the macrophage polarization state. During atherosclerosis regression or stabilization, macrophages switch from M1 proinflammatory phenotype to M2 anti-...

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Detalles Bibliográficos
Autores principales: Saha, Sarmistha, Profumo, Elisabetta, Togna, Anna Rita, Riganò, Rachele, Saso, Luciano, Buttari, Brigitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537694/
https://www.ncbi.nlm.nih.gov/pubmed/33062133
http://dx.doi.org/10.1155/2020/1232816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537694/
https://www.ncbi.nlm.nih.gov/pubmed/33062133
http://dx.doi.org/10.1155/2020/1232816

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