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Lupeol Counteracts the Proinflammatory Signalling Triggered in Macrophages by 7-Keto-Cholesterol: New Perspectives in the Therapy of Atherosclerosis
Macrophage activation and polarization play a central role in atherosclerotic plaque fate. The M1/M2 activation phenotypes represent two profiles of the macrophage polarization state. During atherosclerosis regression or stabilization, macrophages switch from M1 proinflammatory phenotype to M2 anti-...
Autores principales: | Saha, Sarmistha, Profumo, Elisabetta, Togna, Anna Rita, Riganò, Rachele, Saso, Luciano, Buttari, Brigitta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537694/ https://www.ncbi.nlm.nih.gov/pubmed/33062133 http://dx.doi.org/10.1155/2020/1232816 |
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