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3D mapping and accelerated super-resolution imaging of the human genome using in situ sequencing.

That genome function may respond to its three-dimensional (3D) organization highlights the need for methods that can image genomes with superior coverage as well as greater genomic and optical resolution. Here, we push toward this goal by introducing OligoFISSEQ, a suite of three methods that levera...

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Detalles Bibliográficos
Autores principales: Nguyen, Huy Q., Chattoraj, Shyamtanu, Castillo, David, Nguyen, Son C., Nir, Guy, Lioutas, Antonios, Hershberg, Elliot A., Martins, Nuno M. C., Reginato, Paul L., Hannan, Mohammed, Beliveau, Brian J., Church, George M., Daugharthy, Evan R., Marti-Renom, Marc A., Wu, C.-ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537785/
https://www.ncbi.nlm.nih.gov/pubmed/32719531
http://dx.doi.org/10.1038/s41592-020-0890-0