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Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells—A potential mechanism for immune modulation

Human mesenchymal stem/stromal cells (hMSCs) are a promising therapy for acute respiratory distress syndrome (ARDS) and other inflammatory conditions. While considerable research has focused on paracrine effects and mitochondrial transfer that improve lung fluid balance, hMSCs are well known to have...

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Detalles Bibliográficos
Autores principales: Wilfong, Erin M., Croze, Roxanne, Fang, Xiaohui, Schwede, Matthew, Niemi, Erene, López, Giselle Y., Lee, Jae-Woo, Nakamura, Mary C., Matthay, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537876/
https://www.ncbi.nlm.nih.gov/pubmed/33021986
http://dx.doi.org/10.1371/journal.pone.0240319