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Buffering and total calcium levels determine the presence of oscillatory regimes in cardiac cells

Calcium oscillations and waves induce depolarization in cardiac cells which are believed to cause life-threathening arrhythimas. In this work, we study the conditions for the appearance of calcium oscillations in both a detailed subcellular model of calcium dynamics and a minimal model that takes in...

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Detalles Bibliográficos
Autores principales: Marchena, Miquel, Echebarria, Blas, Shiferaw, Yohannes, Alvarez-Lacalle, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537911/
https://www.ncbi.nlm.nih.gov/pubmed/32970668
http://dx.doi.org/10.1371/journal.pcbi.1007728