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Ribosome recycling is not critical for translational coupling in Escherichia coli

We used ribosome profiling to characterize the biological role of ribosome recycling factor (RRF) in Escherichia coli. As expected, RRF depletion leads to enrichment of post-termination 70S complexes in 3′-UTRs. We also observe that elongating ribosomes are unable to complete translation because the...

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Detalles Bibliográficos
Autores principales: Saito, Kazuki, Green, Rachel, Buskirk, Allen R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538156/
https://www.ncbi.nlm.nih.gov/pubmed/32965213
http://dx.doi.org/10.7554/eLife.59974