The Rho-GEF PIX-1 directs assembly or stability of lateral attachment structures between muscle cells

PIX proteins are guanine nucleotide exchange factors (GEFs) that activate Rac and Cdc42, and are known to have numerous functions in various cell types. Here, we show that a PIX protein has an important function in muscle. From a genetic screen in C. elegans, we found that pix-1 is required for the...

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Detalles Bibliográficos
Autores principales: Moody, Jasmine C., Qadota, Hiroshi, Reedy, April R., Okafor, C. Denise, Shanmugan, Niveda, Matsunaga, Yohei, Christian, Courtney J., Ortlund, Eric A., Benian, Guy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538588/
https://www.ncbi.nlm.nih.gov/pubmed/33024114
http://dx.doi.org/10.1038/s41467-020-18852-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538588/
https://www.ncbi.nlm.nih.gov/pubmed/33024114
http://dx.doi.org/10.1038/s41467-020-18852-4

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