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A Semiquantitative Non-invasive Measurement of PcomA Patency in C57BL/6 Mice Explains Variance in Ischemic Brain Damage in Filament MCAo

Numerous studies on experimental ischemic stroke use the filament middle cerebral artery occlusion (fMCAo) model in C57BL/6 mice, but lesion sizes in this strain are highly variable. A known contributor is variation in the posterior communicating artery (PcomA) patency. We therefore aimed to provide...

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Detalles Bibliográficos
Autores principales: Knauss, Samuel, Albrecht, Carolin, Dirnagl, Ulrich, Mueller, Susanne, Harms, Christoph, Hoffmann, Christian Johannes, Koch, Stefan Paul, Endres, Matthias, Boehm-Sturm, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538613/
https://www.ncbi.nlm.nih.gov/pubmed/33071747
http://dx.doi.org/10.3389/fnins.2020.576741