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The Discovery of Insulin-Regulated Aminopeptidase (IRAP) Inhibitors: A Literature Review

Insulin-Regulated Aminopeptidase (IRAP, EC 3.4.11.3) is a multi-tasking member of the M1 family of zinc aminopeptidases. Among its diverse biological functions, IRAP is a regulator of oxytocin levels during late stages of pregnancy, it affects cellular glucose uptake by trafficking of the glucose tr...

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Detalles Bibliográficos
Autores principales: Georgiadis, Dimitris, Ziotopoulou, Angeliki, Kaloumenou, Eleni, Lelis, Angelos, Papasava, Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538644/
https://www.ncbi.nlm.nih.gov/pubmed/33071797
http://dx.doi.org/10.3389/fphar.2020.585838