Cargando…

MALT1 Inhibition as a Therapeutic Strategy in T-Cell Acute Lymphoblastic Leukemia by Blocking Notch1-Induced NF-κB Activation

Current treatment of T-cell acute lymphoblastic leukemia (T-ALL) is primarily based on high-intensity combination chemotherapy, which has serious side effects. Therefore, developments of novel targeted therapeutics are urgently needed for treatment of T-ALL. In this study, we found that mucosa-assoc...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Rong, Zhang, Huihui, Xu, Jiawen, Zhang, Ninghan, Pan, Ting, Zhong, Xiaomin, Zhang, Huanxin, Yin, Lingling, Yao, Yao, Wu, Qingyun, Li, Zhenyu, Liu, Xuejiao, Xu, Kailin, Niu, Mingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538650/
https://www.ncbi.nlm.nih.gov/pubmed/33072583
http://dx.doi.org/10.3389/fonc.2020.558339