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Pituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging

Dopaminergic neurons in the midbrain are of particular interest due to their role in diseases such as Parkinson’s disease and schizophrenia. Genetic variation between individuals can affect the integrity and function of dopaminergic neurons but the DNA variants and molecular cascades modulating dopa...

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Detalles Bibliográficos
Autores principales: Gui, Yujuan, Thomas, Mélanie H., Garcia, Pierre, Karout, Mona, Halder, Rashi, Michelucci, Alessandro, Kollmus, Heike, Zhou, Cuiqi, Melmed, Shlomo, Schughart, Klaus, Balling, Rudi, Mittelbronn, Michel, Nadeau, Joseph H., Williams, Robert W., Sauter, Thomas, Buttini, Manuel, Sinkkonen, Lasse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538689/
https://www.ncbi.nlm.nih.gov/pubmed/33173537
http://dx.doi.org/10.3389/fgene.2020.566734