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Disrupted endothelial cell heterogeneity and network organization impair vascular function in prediabetic obesity

BACKGROUND: Obesity is a major risk factor for diabetes and cardiovascular diseases such as hypertension, heart failure, and stroke. Impaired endothelial function occurs in the earliest stages of obesity and underlies vascular alterations that give rise to cardiovascular disease. However, the mechan...

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Detalles Bibliográficos
Autores principales: Wilson, Calum, Zhang, Xun, Lee, Matthew D., MacDonald, Margaret, Heathcote, Helen R., Alorfi, Nasser M.N., Buckley, Charlotte, Dolan, Sharron, McCarron, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538703/
https://www.ncbi.nlm.nih.gov/pubmed/32791171
http://dx.doi.org/10.1016/j.metabol.2020.154340