LncRNA-BLACAT1 Facilitates Proliferation, Migration and Aerobic Glycolysis of Pancreatic Cancer Cells by Repressing CDKN1C via EZH2-Induced H3K27me3

OBJECTIVE: To investigate the role of lncRNA-BLACAT1 in promoting H3K27 trimethylation of CDKN1C gene by recruiting EZH2 to regulate CCNE on glycolysis and mitochondrial oxidative phosphorylation of pancreatic cancer (PC) cells. METHODS: Following bioinformatic prediction, EZH2 and BLACAT1 in PC cel...

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Detalles Bibliográficos
Autores principales: Zhou, Xin, Gao, Wei, Hua, Huanhuan, Ji, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538708/
https://www.ncbi.nlm.nih.gov/pubmed/33072570
http://dx.doi.org/10.3389/fonc.2020.539805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538708/
https://www.ncbi.nlm.nih.gov/pubmed/33072570
http://dx.doi.org/10.3389/fonc.2020.539805

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