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Consistent opening of the blood brain barrier using focused ultrasound with constant intravenous infusion of microbubble agent

The blood brain barrier (BBB) is a major obstacle to the delivery of therapeutics to the brain. Focused ultrasound (FUS) in combination with microbubbles can non-invasively open the BBB in a targeted manner. Bolus intravenous injections of microbubbles are standard practice, but dynamic influx and c...

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Detalles Bibliográficos
Autores principales: Lapin, Norman A., Gill, Kirt, Shah, Bhavya R., Chopra, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538995/
https://www.ncbi.nlm.nih.gov/pubmed/33024157
http://dx.doi.org/10.1038/s41598-020-73312-9