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Extensive fragmentation and re-organization of transcription in Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE) is the prototype of autoimmune diseases, characterized by extensive gene expression perturbations in peripheral blood immune cells. Circumstantial evidence suggests that these perturbations may be due to altered epigenetic profiles and chromatin accessibility but t...

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Detalles Bibliográficos
Autores principales: Ntasis, Vasilis F., Panousis, Nikolaos I., Tektonidou, Maria G., Dermitzakis, Emmanouil T., Boumpas, Dimitrios T., Bertsias, George K., Nikolaou, Christoforos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539002/
https://www.ncbi.nlm.nih.gov/pubmed/33024230
http://dx.doi.org/10.1038/s41598-020-73654-4