Hyperphosphorylated tau aggregation and cytotoxicity modulators screen identified prescription drugs linked to Alzheimer's disease and cognitive functions

The neurodegenerative Alzheimer’s disease (AD) affects more than 30 million people worldwide. There is thus far no cure or prevention for AD. Aggregation of hyperphosphorylated tau in the brain correlates with the cognitive decline of patients of AD and other neurodegenerative tauopathies. Intracere...

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Detalles Bibliográficos
Autores principales: Liu, Mengyu, Dexheimer, Thomas, Sui, Dexin, Hovde, Stacy, Deng, Xiexiong, Kwok, Roland, Bochar, Daniel A., Kuo, Min-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539012/
https://www.ncbi.nlm.nih.gov/pubmed/33024171
http://dx.doi.org/10.1038/s41598-020-73680-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539012/
https://www.ncbi.nlm.nih.gov/pubmed/33024171
http://dx.doi.org/10.1038/s41598-020-73680-2

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