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Hyperphosphorylated tau aggregation and cytotoxicity modulators screen identified prescription drugs linked to Alzheimer's disease and cognitive functions
The neurodegenerative Alzheimer’s disease (AD) affects more than 30 million people worldwide. There is thus far no cure or prevention for AD. Aggregation of hyperphosphorylated tau in the brain correlates with the cognitive decline of patients of AD and other neurodegenerative tauopathies. Intracere...
Autores principales: | Liu, Mengyu, Dexheimer, Thomas, Sui, Dexin, Hovde, Stacy, Deng, Xiexiong, Kwok, Roland, Bochar, Daniel A., Kuo, Min-Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539012/ https://www.ncbi.nlm.nih.gov/pubmed/33024171 http://dx.doi.org/10.1038/s41598-020-73680-2 |
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