Adaptation and selection shape clonal evolution of tumors during residual disease and recurrence

The survival and recurrence of residual tumor cells following therapy constitutes one of the biggest obstacles to obtaining cures in breast cancer, but it remains unclear how the clonal composition of tumors changes during relapse. We use cellular barcoding to monitor clonal dynamics during tumor re...

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Detalles Bibliográficos
Autores principales: Walens, Andrea, Lin, Jiaxing, Damrauer, Jeffrey S., McKinney, Brock, Lupo, Ryan, Newcomb, Rachel, Fox, Douglas B., Mabe, Nathaniel W., Gresham, Jeremy, Sheng, Zhecheng, Sibley, Alexander B., De Buysscher, Tristan, Kelkar, Hemant, Mieczkowski, Piotr A., Owzar, Kouros, Alvarez, James V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539014/
https://www.ncbi.nlm.nih.gov/pubmed/33024122
http://dx.doi.org/10.1038/s41467-020-18730-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539014/
https://www.ncbi.nlm.nih.gov/pubmed/33024122
http://dx.doi.org/10.1038/s41467-020-18730-z

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