Lipoxin A4 Inhibits NLRP3 Inflammasome Activation in Rats With Non-compressive Disc Herniation Through the JNK1/Beclin-1/PI3KC3 Pathway

BACKGROUND: Non-compressive disc herniation is induced by an inflammatory response from the nucleus pulposus tissue and nerve roots. Lipoxins (LXs) are important endogenous anti-inflammatory mediators in the body, helping to inhibit neutrophil recruitment and stimulate autophagy in monocytes and mac...

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Detalles Bibliográficos
Autores principales: Jin, Jin, Xie, Yonggang, Shi, Cunxian, Ma, Jiahai, Wang, Yihao, Qiao, Leyan, Li, Kezhong, Sun, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539067/
https://www.ncbi.nlm.nih.gov/pubmed/33071721
http://dx.doi.org/10.3389/fnins.2020.00799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539067/
https://www.ncbi.nlm.nih.gov/pubmed/33071721
http://dx.doi.org/10.3389/fnins.2020.00799

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