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Effects of genetic variability of CYP2D6 on neural substrates of sustained attention during on-task activity

The polymorphic drug-metabolizing enzyme CYP2D6, which is responsible for the metabolism of most psychoactive compounds, is expressed not only in the liver, but also in the brain. The effects of its marked genetic polymorphism on the individual capacity to metabolize drugs are well known, but its ro...

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Detalles Bibliográficos
Autores principales: Viviani, Roberto, Messina, Irene, Bosch, Julia E., Dommes, Lisa, Paul, Anna, Schneider, Katharina L., Scholl, Catharina, Stingl, Julia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539151/
https://www.ncbi.nlm.nih.gov/pubmed/33024081
http://dx.doi.org/10.1038/s41398-020-01020-z