Glufosinate constrains synchronous and metachronous metastasis by promoting anti‐tumor macrophages

Glutamine synthetase (GS) generates glutamine from glutamate and controls the release of inflammatory mediators. In macrophages, GS activity, driven by IL10, associates to the acquisition of M2‐like functions. Conditional deletion of GS in macrophages inhibits metastasis by boosting the formation of...

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Detalles Bibliográficos
Autores principales: Menga, Alessio, Serra, Marina, Todisco, Simona, Riera‐Domingo, Carla, Ammarah, Ummi, Ehling, Manuel, Palmieri, Erika M, Di Noia, Maria Antonietta, Gissi, Rosanna, Favia, Maria, Pierri, Ciro L, Porporato, Paolo E, Castegna, Alessandra, Mazzone, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539200/
https://www.ncbi.nlm.nih.gov/pubmed/32885605
http://dx.doi.org/10.15252/emmm.201911210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539200/
https://www.ncbi.nlm.nih.gov/pubmed/32885605
http://dx.doi.org/10.15252/emmm.201911210

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