Zinc inhibits lethal inflammatory shock by preventing microbe‐induced interferon signature in intestinal epithelium

The cytokine TNF drives inflammatory diseases, e.g., Crohn's disease. In a mouse model of TNF‐induced systemic inflammatory response syndrome (SIRS), severe impact on intestinal epithelial cells (IECs) is observed. Zinc confers complete protection in this model. We found that zinc no longer pro...

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Detalles Bibliográficos
Autores principales: Souffriau, Jolien, Timmermans, Steven, Vanderhaeghen, Tineke, Wallaeys, Charlotte, Van Looveren, Kelly, Aelbrecht, Lindsy, Dewaele, Sylviane, Vandewalle, Jolien, Goossens, Evy, Verbanck, Serge, Boyen, Filip, Eggermont, Melanie, De Commer, Lindsey, De Rycke, Riet, De Bruyne, Michiel, Tito, Raul, Ballegeer, Marlies, Vandevyver, Sofie, Velho, Tiago, Moita, Luis Ferreira, Hochepied, Tino, De Bosscher, Karolien, Raes, Jeroen, Van Immerseel, Filip, Beyaert, Rudi, Libert, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539219/
https://www.ncbi.nlm.nih.gov/pubmed/32914580
http://dx.doi.org/10.15252/emmm.201911917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539219/
https://www.ncbi.nlm.nih.gov/pubmed/32914580
http://dx.doi.org/10.15252/emmm.201911917

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