IMPAD1 and KDELR2 drive invasion and metastasis by enhancing Golgi-mediated secretion.

Non-small cell lung cancer (NSCLC) is the deadliest form of cancer worldwide, due in part to its proclivity to metastasize. Identifying novel drivers of invasion and metastasis holds therapeutic potential for the disease. We conducted a gain-of-function invasion screen, which identified two separate...

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Detalles Bibliográficos
Autores principales: Bajaj, Rakhee, Kundu, Samrat T., Grzeskowiak, Caitlin L., Fradette, Jared J., Scott, Kenneth L., Creighton, Chad J., Gibbons, Don L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539228/
https://www.ncbi.nlm.nih.gov/pubmed/32753652
http://dx.doi.org/10.1038/s41388-020-01410-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539228/
https://www.ncbi.nlm.nih.gov/pubmed/32753652
http://dx.doi.org/10.1038/s41388-020-01410-z

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