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Immunoglobulin G Glycoprofiles are Unaffected by Common Bottom-Up Sample Processing

[Image: see text] Immunoglobulin G (IgG) glycosylation is a key post-translational modification in regulating IgG function. It is therefore a prominent target for biomarker discovery and a critical quality attribute of antibody-based biopharmaceuticals. A common approach for IgG glycosylation analys...

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Detalles Bibliográficos
Autores principales: Amez-Martín, Manuela, Wuhrer, Manfred, Falck, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539295/
https://www.ncbi.nlm.nih.gov/pubmed/32945168
http://dx.doi.org/10.1021/acs.jproteome.0c00656