Virtual Screening and Design with Machine Intelligence Applied to Pim‐1 Kinase Inhibitors

Ligand‐based virtual screening of large compound collections, combined with fast bioactivity determination, facilitate the discovery of bioactive molecules with desired properties. Here, chemical similarity based machine learning and label‐free differential scanning fluorimetry were used to rapidly...

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Detalles Bibliográficos
Autores principales: Schneider, Petra, Welin, Martin, Svensson, Bo, Walse, Björn, Schneider, Gisbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539333/
https://www.ncbi.nlm.nih.gov/pubmed/33448694
http://dx.doi.org/10.1002/minf.202000109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539333/
https://www.ncbi.nlm.nih.gov/pubmed/33448694
http://dx.doi.org/10.1002/minf.202000109

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