Therapeutic potential of a novel prodrug of green tea extract in induction of apoptosis via ERK/JNK and Akt signaling pathway in human endometrial cancer

BACKGROUND: Previous studies have shown a major green tea polyphenol (−)-epigallocatechin-3-gallate ((−)-EGCG) as a powerful anti-cancer agent. However, its poor bioavailability and requirement of a high dosage to manifest activity have restricted its clinical application. Recently, our team synthes...

Descripción completa

Detalles Bibliográficos
Autores principales: Man, Gene Chi Wai, Wang, Jianzhang, Song, Yi, Wong, Jack Ho, Zhao, Yu, Lau, Tat San, Leung, Kam Tong, Chan, Tak Hang, Wang, Huating, Kwong, Joseph, Ng, Tzi Bun, Wang, Chi Chiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539473/
https://www.ncbi.nlm.nih.gov/pubmed/33023525
http://dx.doi.org/10.1186/s12885-020-07455-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539473/
https://www.ncbi.nlm.nih.gov/pubmed/33023525
http://dx.doi.org/10.1186/s12885-020-07455-3

Ejemplares similares