Age-associated changes in the circulating human antibody repertoire are upregulated in autoimmunity

BACKGROUND: The immune system undergoes a myriad of changes with age. While it is known that antibody-secreting plasma and long-lived memory B cells change with age, it remains unclear how the binding profile of the circulating antibody repertoire is impacted. RESULTS: To understand humoral immunity...

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Detalles Bibliográficos
Autores principales: Arvey, Aaron, Rowe, Michael, Legutki, Joseph Barten, An, Gang, Gollapudi, Anantha, Lei, Anna, Colston, Bill, Putterman, Chaim, Smith, David, Stiles, Janelle, Tarasow, Theodore, Ramamoorthy, Preveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539520/
https://www.ncbi.nlm.nih.gov/pubmed/33042204
http://dx.doi.org/10.1186/s12979-020-00193-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539520/
https://www.ncbi.nlm.nih.gov/pubmed/33042204
http://dx.doi.org/10.1186/s12979-020-00193-x

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