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Evaluation of neurofilament light chain in the cerebrospinal fluid and blood as a biomarker for neuronal damage in experimental pneumococcal meningitis

BACKGROUND: Pneumococcal meningitis (PM) remains a global public health concern and affects all age groups. If acquired during infancy or childhood, permanent neurofunctional deficits including cognitive impairment, cerebral palsy, and secondary epilepsy are typical sequelae of neuronal injury. Dete...

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Detalles Bibliográficos
Autores principales: Le, Ngoc Dung, Muri, Lukas, Grandgirard, Denis, Kuhle, Jens, Leppert, David, Leib, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539528/
https://www.ncbi.nlm.nih.gov/pubmed/33028339
http://dx.doi.org/10.1186/s12974-020-01966-3