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Evaluation of neurofilament light chain in the cerebrospinal fluid and blood as a biomarker for neuronal damage in experimental pneumococcal meningitis
BACKGROUND: Pneumococcal meningitis (PM) remains a global public health concern and affects all age groups. If acquired during infancy or childhood, permanent neurofunctional deficits including cognitive impairment, cerebral palsy, and secondary epilepsy are typical sequelae of neuronal injury. Dete...
Autores principales: | Le, Ngoc Dung, Muri, Lukas, Grandgirard, Denis, Kuhle, Jens, Leppert, David, Leib, Stephen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539528/ https://www.ncbi.nlm.nih.gov/pubmed/33028339 http://dx.doi.org/10.1186/s12974-020-01966-3 |
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