Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels

Endogenous PIEZO1 channels of native endothelium lack the hallmark inactivation often seen when these channels are overexpressed in cell lines. Because prior work showed that the force of shear stress activates sphingomyelinase in endothelium, we considered if sphingomyelinase is relevant to endogen...

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Detalles Bibliográficos
Autores principales: Shi, Jian, Hyman, Adam J., De Vecchis, Dario, Chong, Jiehan, Lichtenstein, Laeticia, Futers, T. Simon, Rouahi, Myriam, Salvayre, Anne Negre, Auge, Nathalie, Kalli, Antreas C., Beech, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539531/
https://www.ncbi.nlm.nih.gov/pubmed/33027663
http://dx.doi.org/10.1016/j.celrep.2020.108225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539531/
https://www.ncbi.nlm.nih.gov/pubmed/33027663
http://dx.doi.org/10.1016/j.celrep.2020.108225

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