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Improving the therapeutic index in adoptive cell therapy: key factors that impact efficacy
The therapeutic index (TI) is a quantitative assessment of a drug safety proportional to its effectiveness. The estimation is intuitive when the engagement of the product with its target is dependent on stable chemistry and predictable pharmacokinetics as is the case for small molecules or antibodie...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BMJ Publishing Group
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539608/ https://www.ncbi.nlm.nih.gov/pubmed/33023983 http://dx.doi.org/10.1136/jitc-2020-001619 |