Glioma Cells With Genetically Engineered IGF-I Receptor Downregulation Can Persist in the Brain in a Dormant State

Glioblastoma multiforme is an aggressive malignancy, resistant to standard treatment modalities and associated with poor prognosis. We analyzed the role of the IGF system in intracerebral glioma growth using human and rat glioma cells. The glioma cells C6 and U87MG were transduced with a genetically...

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Detalles Bibliográficos
Autores principales: Samani, Amir A., Nalbantoglu, Josephine, Brodt, Pnina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539665/
https://www.ncbi.nlm.nih.gov/pubmed/33072581
http://dx.doi.org/10.3389/fonc.2020.555945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539665/
https://www.ncbi.nlm.nih.gov/pubmed/33072581
http://dx.doi.org/10.3389/fonc.2020.555945

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