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Role of ACE2 receptor and the landscape of treatment options from convalescent plasma therapy to the drug repurposing in COVID-19

Since the first case reports in Wuhan, China, the SARS-CoV-2 has caused a pandemic and took lives of > 8,35,000 people globally. This single-stranded RNA virus uses Angiotensin-converting enzyme 2 (ACE2) as a receptor for entry into the host cell. Overexpression of ACE2 is mainly observed in hype...

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Detalles Bibliográficos
Autores principales: Kumar, Pravindra, Sah, Ashok Kumar, Tripathi, Greesham, Kashyap, Anjali, Tripathi, Avantika, Rao, Rashmi, Mishra, Prabhu C., Mallick, Koustav, Husain, Amjad, Kashyap, Manoj Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539757/
https://www.ncbi.nlm.nih.gov/pubmed/33029696
http://dx.doi.org/10.1007/s11010-020-03924-2